Publications

[2024]

80. Discovery and Optimization of a Series of Vinyl Sulfoximine-Based Analogues as Potent Nrf2 Activators for the Treatment of Multiple Sclerosis. Journal of Medicinal Chemistry 2023; 67: 17866-17892

[2023]

79. Structure-based drug discovery of corticotropin-releasing hormone receptor 1 antagonist using X-ray free-electron laser. Experimental and Molecular Medicine 2023; 55: 2039-2050

78. Exploration of Tetrahydroisoquinoline- and Benzo[c]azepine-Based Sphingosine 1-Phosphate Receptor 1 Agonists for the Treatment of Multiple Sclerosis. Journal of Medicinal Chemistry 2023; 66: 10381-10412

77. Park, H., Cho, Y., Lee, J.E., Lee, K.M., Lee, J. Bahn, Y.S., Son, J. Evaluation and Monitoring of the Natural Toxin Ptaquiloside in Bracken Fern, Meat, and Dairy Products. Toxins 2023; 15:231

76. Lee, K.M., Han, S.M., Lee, H.J., Kang, M., Jeong T.Y., Son, J., Min, H., Cha, S., Oh, H.B., Oh, W.G., Lee, J.* Influence of mobile phase composition on the analytical sensitivity of LC–ESI–MS/MS for the concurrent analysis of bisphenols, parabens, chlorophenols, benzophenones, and alkylphenols. Environmental Research 2023; 221: 115305

[2022]

75. Lee, S., Lee, K.M., Han, S.M., Lee, H.J., Sung, C., Min, H., Im, H., Han, S.B., Cha, S., Lee, J.* Comprehensive LC-MS/MS Method Combined with Tandem Hybrid Hydrolysis for Multiple Exposure Assessment of Multiclass Environmental pollutants. Environmental Research 2022; 211: 113053

74. Park, S.J., Yeon, S.K., Kim, Y., Kim, H.J., Kim, S., Kim, J., Choi, J.W., Kim, B., Lee, E.H., Kim, R., Seo, S.H., Lee, J., Kim, J.W., Hwang, H., Park, J.H., Park, K.D. Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis. Journal of Medicinal Chemistry 2022; 65: 3539-3562

[2021]

73. Lee, K.M., Han, S.M., Lee, S., Jeong, T.Y., Kim, H.J., Min, H., Kim, L.H., Cha, S., Oh, W.K., Lee, J.* Fluoride-assisted liquid chromatography-tandem mass spectrometry method for simultaneous analysis of propofol and its metabolites without derivatization in urine. Journal of Chromatography A 2021; 1652: 462360

[2020]

72. Choi, S.M., Kim, Y.A., Lee, J., Kim, J.H., Lee, T., Min, B.S., Kim, J.A., Lee, S. Characterization of hydrocoptisonine metabolites in human liver microsomes using a high-resolution quadrupole-orbitrap mass spectrometer. Xenobiotica 2020; 50: 1423-1433

71. Kwak, H., Koh, W., Kim, S., Song, K., Shin, J.I., Lee, J.M., Lee, Elliot H., Bae, J.Y., Ha, G.E., Oh, J.E., Park, Y. Mason, Kim, S., Feng, J., Lee, S.E., Choi, J.W., Kim, K.H., Kim, Y.S., Woo, J., Lee, D., Son, T., Kwon, S.W., Park, K.D., Yoon, B.E., Lee, J., Li, Y., Lee, H., Bae, Y.C., Lee, C. Justin, Cheong, E. Astrocytes control sensory acuity via tonic inhibition in the thalamus. Neuron 2020; 108(4): 691-706

70. Rahaman, K.A., Hasan, M., Seo, J.E., Muresan, A.R., Song, H.J., Min, H., Son, J., Lee, J., Lee, J., Kim, B., Kwon, O.S. Inhibition of LAT-1 transporter increases luminal leucine concentration which increases disease symptoms via increased T cells and LAT-1 mRNA in the brains of experimental autoimmune encephalomyelitis mouse models. Journal of Pharmaceutical Investigation 2020; 50: 481-491

69. Kim, G., Choi, H.K., Lee, H., Moon, K.S., Oh, J.H., Lee, J., Shin, J.G., Kim, D.H. Increased hepatic acylcarnitine after oral administration of amiodarone in rats. Journal of Applied Toxicology 2020; 40: 1004-1013

68. Kim, S., Indu Viswanath, A.N., Park, J.H., Lee, H.E., Park, A.Y., Choi J.W., Kim, H.J., Londhe, A.M., Jang, B.K., Lee, J., Hwang, H., Lim, S.M., Pae, A.N., Park, K.D. Nrf2 activator via interference of Nrf2-Keap1 interaction has antioxidant and anti-inflammatory properties in Parkinson's disease animal model. Neuropharmacology 2020; 167: 107989

67. Cho, H.D., Kim, J., Lee, J.Y., Kim, Y.Y., Lee, Y., Jo, E., Suh, J.H., Lee, J., Cha, S., Han, S.B. A novel dried blood spots analysis combined with on-spot reaction for determination of trimethylamine N-oxide and its related compounds. Talanta 2020; 210: 120639

66. Kim, Y., Shrestha, R., Kim, S., Kim, J.A., Lee, J., Jeong, T.C., Kim, J.H., Lee, S. In vitro characterization of glycyrol metabolites in human liver microsomes using HR-resolution MS spectrometer coupled with tandem mass spectrometry. Xenobiotica 2020; 50: 380-388

65. An, J., Kim, Y.Y., Cho, H.D., Kim, J., Lee, J.Y., Lee, Y., Lee, J., Cha, S., Han, S.B. Development and investigation of a QuEChERS-based method for determination of phthalate metabolites in human milk. Journal of Pharmaceutical and Biomedical Analysis 2020; 181: 113092

[2019]

64. Lee, S., Kim, H.W., Han, S.M., Han, S.Y., Kim, B., Moon, M.H., Kim, K.H., Lee, J.* The performance investigation of bimodal cation exchange/hydrophilic interaction liquid chromatography-electrospray ionization mass spectrometry by modifying mobile phase composition in amino acid separation. Bulletin of the Korean Chemical Society 2019; 40: 775-779

63. Choi, J.W., Kim, S., Park, J.H., Kim, H.J., Shin, S.J., Kim, J.W., Woo, S.Y., Lee, C., Han, S.M., Lee, J., Pae, A.N., Han, G., Park, K.D. Optimization of vinyl sulfone derivatives as potent Nrf2 activators for parkinson's disease therapy. Journal of Medicinal Chemistry 2019; 62: 811-830

[2018]

62. Lee, Y., Seo, E., Park, J.Y., Bae, K.H., Lee, J., Cha, S. Multi-class analysis of exposure chemicals in deciduous teeth by liquid chromatography-mass spectrometry: Preliminary studies on sample preparation methods. Mass Spectrometry Letters 2018; 9: 110-114

61. Kim, Y., Jeon, M., Min, H., Son, J., Lee, J., Kwon, O.S., Kim, K.H. Development of a multi-functional concurrent assay using weak cation exchange solid phase extraction (WCX-SPE) and reconstitution with a diluted sample aliquot for anti-doping analysis. Rapid Communications in Mass Spectrometry 2018; 32: 897-905

60. Lee, J., Lee, S., Kim, B., Lee, J., Kwon, O.S., Cha, E. Direct Quantitation of Amino Acids in Human Serum Using Stepwise-Dilution Strategy and a Mixed-Mode Liquid Chromatography-Tandem Mass Spectrometry. Mass Spectrometry Letters 2018; 9: 30-36

59. Jeong, E.S., Cha, E., Han, S.B., Cha, S., Son, J., Kim, S., Oh, H.B., Lee, J.* Ionization of Gas-Phase Polycyclic Aromatic Hydrocarbons in Electrospray Ionization Coupled with Gas Chromatography. Analytical Chemistry 2018; 90: 4203-4211

[2017]

58. Cha, E., Jeong, E.S., Cha, S., Kim, S., Oh, H.B., Kwon, O.S., Lee, J.* Online Simultaneous Hydrogen/Deuterium Exchange of Multitarget Gas-Phase Molecules by Electrospray Ionization Mass Spectrometry Coupled with Gas Chromatography. Analytical Chemistry 2017; 89: 12284-12292

57. Kim, Y., Jeong, D., Min H., Sung, C., Park, J.H., Son, J., Lee, K.M., Kim, H.J., Lee, J., Kwon, O.S., Kim, K.H. Method for Screening and Confirming Meldonium in Human Urine by High-Resolution Mass Spectrometry and Identification of Endogenous Interferences for Anti-Doping Testing. Mass Spectrometry Letters 2017; 8(2): 39-43

56. Cha, E., Jeong, E.S., Cha, S., Lee, J.* Coupling of gas chromatography and electrospray ionization high resolution mass spectrometry for the analysis of anabolic steroids as trimethylsilyl derivatives in human urine. Analytica Chimica Acta 2017; 964: 123-133

55. Kim, S.M., Noh, M.Y., Kim, H., Cheon, S.Y., Lee, K.M., Lee, J., Cha, E., Park, K.S., Lee, K.W., Sung, J.J., Kim, S.H. 25-Hydroxycholesterol is involved in the pathogenesis of amyotrophic lateral sclerosis. Oncotarget 2017; 8: 11855-11867

[2016]

54. Kim, Y., Min H., Sung, C., Park, J.H., Son, J., Lee, K.M., Kim, H.J., Lee, J., Kwon, O.S., Kim, K.H. Analysis of Glycerol with Isolation of Endogenous Interferences Using “Dilute and Shoot” Strategy and High-Resolution Mass Spectrometry in Human Urine for Antidoping Testing. Mass Spectrometry Letters 2016; 7(4): 111-115

53. Cha, E., Lee, K.M., Park, K.D., Park, K.S., Lee, K.W., Kim, S.M., Lee, J.* Hydroxycholesterol Levels in the Serum and Cerebrospinal Fluid of Patients with Neuromyelitis Optica Revealed by LC-Ag+CIS/MS/MS and LC-ESI/MS/MS with Picolinic Derivatization: Increased Levels and Association with Disability during Acute Attack. PLoS One 2016; 11(12): e0167819. doi:10.1371/journal.pone.0167819

52. Han, J.S., Rahaman, K.A., Seo, J.E., Hasan, M., Lee, K.T., Min, H., Lee, K.M., Park, J.H., Kim, H.J., Kim, K.H., Son, J., Lee, J., Kwon, O.S. Human chorionic gonadotropin (hCG) sub-chronic administration mediated MMP-9 activities and cytokine association deteriorate experimental autoimmune encephalomyelitis (EAE) condition in mice model. Journal of Pharmaceutical Investigation 2016; 46: 685-695

51. Kim, S., Park, M., Yang, H., Dangol, M., Lahiji, S.F., Huh, I., Kim, M., Lee, J., Son, J., Jung, H. Development of a quantitative method for active epidermal growth factor extracted from dissolving microneedle by solid phase extraction and liquid chromatography electrospray ionization mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis 2016; 131: 297-302

50. Min H., Han, B., Sung, C., Park, J.H., Lee, K.M., Kim, H.J., Kim, K.H., Son, J., Kwon, O.S., Lee, J.* LC-MS/MS Method for Simultaneous Analysis of Growth Hormone-Releasing Peptides and Secretagogues in Human Urine. Mass Spectrometry Letters 2016; 7(3): 55-63

49. Jeong, E.S., Kim, K.H., Cha, E., Kwon, O.S., Lee, J.* Direct and rapid quantitation of ephedrines in human urine by paper spray ionization/high resolution mass spectrometry. Journal of Chromatography B. 2016; 1028: 237-241

48. Seo, J.E., Hasan, M., Han, J.S., Kim, N.K., Lee, J.E., Lee, K.M., Park, J.H., Kim, H.J., Son J.H., Lee, J., Kwon, O.S. Dependency of Experimental Autoimmune Encephalomyelitis Induction on MOG35–55 Properties Modulating Matrix Metalloproteinase-9 and Interleukin-6. Neurochemical Research 2016; 41: 666-676

47. Cha, E., Kim, S., Kim, H.W., Lee, K.M., Kim, H.J., Kwon, O.S., Lee, J.* Relationships between structure, ionization profile and sensitivity of exogenous anabolic steroids under electrospray ionization and analysis in human urine using liquid chromatography–tandem mass spectrometry. Biomedical Chromatography 2016; 30: 555-565

46. Cha, E., Kim, S., Lee, K.M., Kim, H.J., Kim, K.H., Lee, J.* Relationship between chromatographic resolution and amide structure of chiral 2-hydroxy acids as O-(−)-menthoxycarbonylated diastereomeric derivatives for enantiomeric separation on achiral gas chromatography. Journal of Chromatography B. 2016; 1012: 17-22

[2015]

45. Cha, E., Kim, S., Kim, H.J., Lee, K.M., Kim, K.H., Kwon, O.S., Lee, J.* Sensitivity of GC-EI/MS, GC-EI/MS/MS, LC-ESI/MS/MS, LC-Ag+CIS/MS/MS, and GC-ESI/MS/MS for analysis of anabolic steroids in doping control. Drug Testing and Analysis 2015; 7: 1040-1049

44. Jeong, E.S., Kim, S.H., Cha, E.J., Lee, K.M., Kim, H.J., Lee, S.W., Kwon, O.S., Lee, J.* Simultaneous analysis of 220 prohibited substances in human urine by ultra-fast liquid chromatography/tandem mass spectrometry in doping control. Rapid Communications in Mass Spectrometry 2015; 29: 367-384

43. Lee, J., Yoon, H.R. Rapid Diagnosis of metabolic disorders based on achiral separation by gas chromatography with a dual column. Analytical Letters 2015; 48: 231-240

[2014]

42. Kim, S.H., Cha, E.J., Lee, K.M., Kim, H.J., Lee, J.* Simultaneous ionization and analysis of 84 anabolic androgenic steroid in human urine using Liquid chromatography-silver ion coordination ionspray/triple-quadrupole Mass spectrometry. Drug Testing and Analysis 2014; 6: 1174-1185

41. Lee, K.M., Kim, H.J., Son, J., Park, J.H., Kwon, O.S., Lee, J.* Simple quantitation of formoterol and 11-nor- Δ9-tetrahydrocannabinol-9-carboxylic acid in human urine by liquid chromatography-tandem mass spectrometry in doping control. Journal of Chromatography B 2014; 967: 8-12

40. Song, M., Lee, D., Kim, S., Bae, J.S., Lee, J., Gong, Y.D., Lee, T., Lee, S.K. Identification of Metabolites of N-(5-Benzoyl-2-(4-(2-Methoxyphenyl)piperazin-1-yl)thiazol-4-yl)pivalamide Including CYP3A4-Mediated C-Demethylation in Human Liver Microsomes with High-Resolution/High-Accuracy Tandem Mass spectrometry. Drug Metabolism and Dispositions 2014; 42: 1252-1260

39. Kim, Y., Kim, U., Kim, I.S., Lee, S.H., Lee, J., Kim, D.H., Yoo, H.H. Absorption, distribution, metabolism and excretion of gemigliptin, a novel dipeptidyl peptidase IV inhibitor, in rats. Xenobiotica 2014; 44(7): 627-634

38. Woo, S.Y., Kim, J.H., Moon, M.K., Han, S.H., Yeon, S.K., Choi, J.W., Jang, B.K., Song, H.J., Kang, Y.G., Kim, J.W., Lee J., Kim, D.J., Hwang, O., Park, K.D. Discovery of Vinyl Sulfones as a Novel Class of Neuroprotective Agents toward Parkinson's Disease Therapy. Journal of Medicinal Chemistry 2014; 57: 1473-1487

[2013]

37. Choi, M.J., No, E.S., Thorat, D.A., Jang, J.W., Yang, H., Lee, J., Choo, H., Kim, S.J., Lee, C.S., Ko, S.Y., Lee, J., Nam, G., Pae, A.N. Synthesis and Biological Evaluation of Aryloxazole Derivatives as Antimitotic and Vascular-Disrupting Agents for Cancer Therapy. Journal of Medicinal Chemistry 2013; 56(22): 9008-9018

36. Kim, S.H., Yoo, H.H., Cha, E.J., Jeong, E.S., Kim, H.J., Kim, D.H., Lee, J.* Ultra-fast generic LC-MS/MS method for high-throughput quantification in drug discovery. Mass Spectrometry Letters 2013; 4(3): 47-50

35. Park, H.R., Kim, J., Kim, T., Jo, S., Yeom, M., Moon, B., Choo, I.H., Lee, J., Lim, E.J., Park, K.D., Min, S.J., Nam, G., Keum, G., Lee, C.J., Choo, H. Oxazolopyridines and thiazolopyridines as monoamine oxidase B inhibitors for the treatment of parkinson’s diease. Bioorganic & Medicinal Chemistry 2013; 21: 5480-5487

34. Yang, H.Y., Tae, J., Seo, Y.W., Kim, Y.J., Im, H.Y., Choi, G.D., Cho, H., Park, W.K., Kwon, O.S., Cho, Y.S., Ko, M., Jang, H., Lee, J., Choi, K., Kim, C.H., Lee, J., Pae, A.N. Novel pyrimidoazepine analogs as serotonin 5-HT2A and 5-HT2C receptor ligands for the treatment of obesity. European Journal of Medicinal Chemistry 2013; 63: 558-569

33. Lee, S., Lee, J., Jahng, Y., Jeong, T.C., Kim, D.H. Characterization of in vitro metabolites of luotonin A in human liver microsomes using electrospray/tandem mass spectrometry. Xenobiotica 2013; 43(6): 527-533

32. Jin, M.J., Lee, J., In. M.K., Yoo. H.H. Characterization of in vitro metabolites of CP 47,497, a synthetic cannabinoid, in human liver microsomes by LC-MS/MS. Journal of Forensic Sciences 2013; 58(1): 195-199

[2012]

31. Kim, S.H. †, Kim, H.J. †, Son, J. †, Jeon, B.W., Jeong, E.S., Cha, E.J., Lee, J.* Simultaneous determination of synthetic phosphodiesterase-5 inhibitors in dietary supplements by liquid chromatography-high resolution/mass spectrometry. Mass Spectrometry Letters 2012; 3(2): 50-53

30. Kim, U., Jin, M.J., Lee, J., Han, S.B., In. M.K., Yoo. H.H. Tentative identification of phase I metabolites of HU-210, a classical synthetic cannabinoids, by LC-MS/MS. Journal of Pharmaceutical and Biomedical Analysis 2012; 64-65: 26-34

[2011]

29. Jeon, B.W., Yoo, H.H., Jeong, E.S., Kim, H.J., Jin C., Kim, D.H., Lee, J.* LC-MS/MS method for rapid screening and confirmation of 44 exogenous anabolic steroids in human urine. Analytical and Bioanalytical Chemistry 2011; 401: 1353-1363

28. Lee, K.M., Kim, H.J., Jeong, E.S., Yoo. H.H., Kwon, O.S., Jin C., Kim. D.H., Lee, J.* Rapid and accurate quantitative analysis of seven prohibited threshold substances in human urine by liquid chromatography-tandem mass spectrometry in doping control. Rapid Communications in Mass Spectrometry 2011; 25: 2261-2267

27. Lee, K.M., Kim, H.J., Jeong, E.S., Yoo. H.H., Kwon, O.S., Jin C., Kim. D.H., Lee, J.* Validation and applications of gas chromatography-combustion/isotope ratio mass spectrometric method to control misuse of androgens in human. Mass Spectrometry Letters 2011; 2: 33-36.

26. Kim, Y., Kim, U.Y., In, M.K., Lee, J., Kwon, O.S., Yoo. H.H. Hydrophilic interaction chromatography-tandem mass spectrometry method for identification and quantitation of 5-MeO-DIPT and its metabolites in rat urine. Bulletin of the Korean Chemical Society 2011; 32: 1158-1164.

[2008 ~ 2010]

25. Lee, S.K.†, Kim, S.H.†, Kim, H.J., Yoo, H.H., Kwon, O.S., In, M.K., Jin, C., Kim, D.H., Lee, J.* Simultaneous quantitative and qualitative method using liquid chromatography selected reaction monitoring-triggered quantitation-enhanced data-dependent tandem mass spectrometry for the identification and classification of amphetamine-type stimulants abuser in human urine. Rapid Communications in Mass Spectrometry 2010; 24: 3139-3145.

24. Lee, S.K., Kim, H.J., Jin, C., Lee, J.* Formation of unusual [M+H-11 Da]+ ion peak in the collision-induced dissociation mass spectrum of [M+H]+ ion of hydrochlorothiazide. Journal of Mass Spectrometry 2009; 44: 1538-1541.

23. Yoo, H.H., Kim, N.S., Lee, J., Sohn, D.R., Jin, C., Kim, D.H. Characterization of human cytochrome P450 enzymens involved in the biotransformation of eperisone. Xenobiotica 2009; 39: 1-10.

22. Yoo, H.H., Chung, H.J., Lee, J., Lee, C.S., Kang, M.J., Kim, D.H. Enzymatic C-demethylation of 1-[2-(5-tert-butyl-[1, 3, 4] oxadiazole-2-carbonyl)-4-fluoro-pyrrolidin-1-yl]-2-(2-hydroxy-1, 1-dimethyl-ethylamino)-ethanone (LC15—133) in rat liver microsomes. Drug Metabolism and Disposition 2008; 36: 485-489.

[2005 ~ 2007]

21. Lee, J.H., Choi, B.S., Chang, J.H., Lee, H.B., Yoon, J.Y., Lee, J., Shin H. The decarboxylative blaise reaction. Journal of Organic Chemistry 2007; 72: 10261-10263.

20. Lee, J., Xu, Y., Chen, Y., Sprung, R., Kim, S.C., Xie, S., Zhao, Y. Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS. Molecular and Cellular Proteomics 2007; 6: 669-676.

19. Lee, J., Yoo, H.H., Rhim Kang Jin, Sohn, D.R., Kim, D.H. Metabolism and excretion of 5-ethyl-2-{5-[4-(2-hydroxy-ethyl)-piperazine-1-sulfonyl]-2-propoxy-phenyl}-7-propyl-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one (SK3530) in rats. Rapid Communications in Mass Spectrometry 2007; 21: 1139-1149.

18. Kim, S.C., Chen, Y., Mirza, S.M., Xu, Y., Lee, J., Liu, P., Zhao, Y. A clean, more efficient method for in-solution digestion of protein mixtures without detergent or urea. Journal of Proteome Research 2006; 5: 3446-3452.

17. Yoo, H.H., Son, J., Lee, J., Kim, N.S., Shin, M., Kang, M.J., Kim, D.H. The metabolism and excretion of 2-methylaminoethoxy carbonyl-4,4’-dimethoxy-5,6,5’,6’-dimethylenedioxybiphenyl-2’-carboxylic acid (DDB-S) in rats and human. Rapid Communications in Mass Spectrometry 2006; 20: 1981-1988.

16. Lee, J., Yoo, B.C., Lee, H.S., Yoo, H.W., Yoo, H.H., Kang, M.J., Kim, D.H. Rapid quantitative determination of L-FMAU-TP from human peripheral-blood mononuclear cells of hepatitis B virus-infected patients treated with L-FMAU by ion-pairing, reverse-phase, liquid chromatography/electrospray tandem mass spectrometry. Therapeutic Drug Monitoring 2006; 28: 131-137.

15. Lee, J., Yoo, H.H., Kang, M.Y., Kim, D.H. Low-energy collision-induced dissociation of sildenafil thiono analogue: Gas-phase intramolecular nucleophilic substitution through ion-neutral complexes between a cationic substrate and a thione-containing neutral nucleophile. Rapid Communications in Mass Spectrometry 2005; 19: 1767-1770.

14. Lee, S.K., Jin, C.H., Hyun, S.H., Lee, D.W., Kim, G.H., Joen, T.W., Lee, J., Kim, D.H., Jeong, H.G., Lee, E.S., Jeong, T.C. Identification of glutathione conjugates and mercapturic acid 1,2-dibromopropane in female BALB/c mice by liquid chromatography-electrospray tandem mass spectrometry. Xenobiotica 2005; 35: 97-105.

[2000 ~ 2004]

13. Lee, S.K., Kim, N.H., Lee, J., Kim, D.H., Lee, E.S., Choi, H.G., Chang, H.W., Jahng, Y., Jeong, T.C. Induction of cytochrome P450s by rutaecarpine and metabolism of rutaecarpine by cytochrome P450s. Planta Medica 2004; 70: 753-757.

12. Son, J., Lee, J., Lee, M., Lee, E., Lee, J.H., Lee, K.T., La, S., Yang, R., Kim, D.H. Rapid quantitative analysis of oxiracetam in human plasma by liquid chromatography/tandem mass spectrometry with multiple reaction monitoring. Journal of Pharmaceutical and Biomedical Analysis 2004; 35: 183-187.

11. Lee, J., Son, J., Chung, S.J., Kim, D.H. In vitro and in vivo metabolic pathway of pyronaridine characterized by low-energy collision induced dissociation mass spectrometry. Journal of Mass Spectrometry 2004; 39: 1036-1043.

10. Lee, J., La, S., Ahn, B.R., Jeong, T.C., Kim, D.H. Metabolism of 1-{3-[3-(4-cyanobenzyl)-3H-imidazole-4-yl]-propyl}-3-(6-methoxypyridin-3-yl)-1-(2-trifluoromethylbenzyl) thiourea (YH3945), a novel anti-cancer drug, in rats using the 14C-labeled compound. Rapid Communications in Mass Spectrometry 2004; 18: 1901-1910.

9. Lee, S.K., Lee, J., Lee, E.S., Jahng, Y., Kim, D.H., Jeong, T.C. Characterization of in vitro metabolites of rutaecarpine in rat liver microsomes using liquid chromatography/ tandem mass spectrometry. Rapid Communications in Mass Spectrometry 2004; 18: 1073-1080.

8. Son, J., Lee, J., Han, C.K., Kwak, W.J., Yang, R., Kim, D.H. Simultaneous quantitation of loganin and sweroside in plasma using column-switching high-performance liquid chromatography. Analytica Chimica Acta 2004; 503: 257-262.

7. Lee, J., Son, J., Rhee, S.W., Kim, D.H. Absorption, distribution, metabolism and excretion of telmesteine, a mucolitic agent, in rat. Xenobiotica 2003; 33: 755-765.

6. Lee, J., Son, J., Lee, M., Lee, K.T., Kim, D.H. Simultaneous quantitation of enalapril and enalaprilat in human plasma by 96-well solid-phase extraction and liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry 2003; 17: 1157-1162.

5. Lee, J., Son, J., Koh, H.Y., Pae, A.N., Kim, D.H. Rapid analysis of metabolic stability of dopamine receptor antagonists and detection of their metabolites by liquid chromatography/tandem mass spectrometry. Analytical Biochemistry 2003; 313: 292-300.

4. Lee, J., Seo, J.H., Kim, D.H. Determination of tizanidine in human plasma by gas chromatography-mass spectrometry. Analyst 2002; 127: 917-920.

3. Lee, J., Kim, K.R., Won, S., Kim, J.H., Goto, J. Enantioseparation of amino acids as the N(O,S)-ethyloxycarbonyl diastereomeric esters by achiral dual-capillary column gas chromatography. Analyst 2001; 126: 2128-2133.

2. Kim, K.R., Lee, J., Ha, D., Kim, J.H. Configurational analysis of chiral acids as O-trifluoroacetylated (-)-menthyl esters by achiral dual-capillary column gas chromatography. Journal of Chromatography A. 2000; 891: 257-266.

1. Kim, K.R., Lee, J., Ha, D., Jeon, J., Park, H.G., Kim, J.H. Enantiomeric separation and discrimination of 2-hydroxy acids as O-trifluoroacetylated (S)-()-3-methyl-2-butyl esters by achiral dual-capillary column gas chromatography. Journal of Chromatography A. 2000; 874: 91-100.